Fig. 1 · Structure
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Tesmilifene fumarate
H1C Receptor Antagonist
Tesmilifene fumarate is an H1C receptor antagonist that enhances the efficacy of various cytotoxic agents while providing some degree of protection to normal cells. This compound is valuable in chemotherapy research, as it may improve the therapeutic index of anticancer drugs by minimizing their adverse effects on healthy tissue. Tesmilifene fumarate is primarily utilized in studies aimed at optimizing cancer treatment regimens involving combination therapies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1185241-83-1 |
| Applications | H1C Receptor Antagonist |
| Formula | C23H29NO5 |
| Molecular Weight | 399.48 |
| Synonyms | DPPE fumarate |
| SMILES | CCN(CC)CCOC1=CC=C(CC2=CC=CC=C2)C=C1.O=C(O)/C=C/C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.