Fig. 1 · Structure
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Tetrahydrodeoxycorticosterone
GABAA Receptor PMA
Tetrahydrodeoxycorticosterone is a neurosteroid that functions as a potent positive allosteric modulator of the GABAA receptor. This compound exhibits significant neuroinhibitory properties, making it a valuable tool for research focused on the modulation of neuronal excitability and investigation of neuropharmacological mechanisms. Its application includes studies on anxiety, depression, and other conditions associated with GABAergic dysfunction.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 567-03-3 |
| Applications | GABAA Receptor PMA |
| Formula | C21H34O3 |
| Molecular Weight | 334.49 |
| Synonyms | Tetrahydro-11-deoxycorticosterone |
| SMILES | C[C@@]12[C@@H](C(CO)=O)CC[C@@]1([H])[C@]3([H])CC[C@]4([H])C[C@H](O)CC[C@]4(C)[C@@]3([H])CC2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.