Fig. 1 · Structure
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Tetrahydrofolic acid trihydrochloride
Folate Derivative
Tetrahydrofolic acid trihydrochloride is a biologically active derivative of vitamin B9, folate, primarily involved in one-carbon metabolism. This compound acts as a critical donor of one-carbon units essential for the biosynthesis of amino acids, nucleic acids, and lipids. It also functions as an acceptor of free formaldehyde, yielding 5,10-methylenetetrahydrofolate. Tetrahydrofolic acid trihydrochloride is widely utilized in biochemical research and clinical studies related to folate metabolism and its implications in human health.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 150731-85-4 |
| Applications | Folate Derivative |
| Formula | C19H26Cl3N7O6 |
| Molecular Weight | 554.81 |
| Synonyms | L-5,6,7,8-Tetrahydrofolic acid trihydrochloride; L-Tetrahydrofolic acid trihydrochloride |
| SMILES | NC(NC1=C2NC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)CN1)=NC2=O.Cl.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.