Fig. 1 · Structure
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Tetrahydrofolic acid
Folate Derivative
Tetrahydrofolic acid, a biologically active derivative of vitamin B9 (folate), acts as a crucial one-carbon donor in numerous metabolic pathways. It is integral to the synthesis of amino acids, nucleic acids, and lipids, facilitating important biosynthetic processes. Tetrahydrofolic acid also functions as an acceptor of free formaldehyde, leading to the formation of 5,10-methylenetetrahydrofolate. This compound is essential in research applications focused on cellular metabolism, folate-dependent pathways, and the investigation of related biochemical disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 135-16-0 |
| Applications | Folate Derivative |
| Formula | C19H23N7O6 |
| Molecular Weight | 445.43 |
| Synonyms | L-5,6,7,8-Tetrahydrofolic acid; L-Tetrahydrofolic acid |
| SMILES | NC(NC1=C2NC(CNC3=CC=C(C(N[C@@H](CCC(O)=O)C(O)=O)=O)C=C3)CN1)=NC2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.