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Tetramethylpyrazine nitrone

Tetramethylpyrazine Derivative

Tetramethylpyrazine nitrone is a nitrone derivative of tetramethylpyrazine that acts as a potent scavenger of free radicals. It demonstrates neuroprotective activity in ischemic stroke models in both rats and monkeys. In addition, tetramethylpyrazine nitrone has been shown to suppress the overexpression of the neuroinflammatory marker vimentin, making it a valuable candidate for research into neurodegenerative diseases and inflammation-related conditions.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1083171-75-8
Applications	Tetramethylpyrazine Derivative
Formula	C₁₂H₁₉N₃O
Molecular Weight	221.30
Synonyms	TBN
SMILES	CC1=C(C)N=C(C)C(/C=[N+](C(C)(C)C)\[O-])=N1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.