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Tetrazanbigen

Antineoplastic Agent

Tetrazanbigen is a selective antineoplastic agent that demonstrates significant antitumor efficacy across multiple human cancer cell lines, exhibiting IC50 values ranging from 2.13 to 8.01 μg/mL, while sparing normal hepatocytes with an IC50 of 11.25 μg/mL. This compound induces S phase cell cycle arrest and promotes apoptosis specifically in QGY-7701 cells. Tetrazanbigen's antitumor activity is attributed to its ability to stimulate lipid accumulation within cancer cells, presenting valuable applications in cancer research and therapeutic development.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2121990-04-1
Applications	Antineoplastic Agent
Formula	C₁₈H₁₆N₄
Molecular Weight	288.35
Synonyms	TNBG
SMILES	C1(N=C2N3CCC4=C(C=CC=C4)C3CN=C2N5)=C5C=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.