Fig. 1 · Structure

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Tezacitabine hydrate

Ribonucleotide Reductase Inhibitor

Tezacitabine hydrate is a potent ribonucleotide reductase inhibitor that exhibits both cytostatic and cytotoxic properties as a nucleoside analogue. By irreversibly inhibiting ribonucleotide reductase, it disrupts DNA replication and repair processes, effectively inducing apoptosis in target cells. Tezacitabine hydrate shows promise for therapeutic applications in the treatment of leukemias and various solid tumors, including carcinomas.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 171176-43-5
Applications Ribonucleotide Reductase Inhibitor
Formula C10H14FN3O5
Molecular Weight 275.23
SMILES
O[C@H]([C@@H](CO)O[C@H]/1N2C(N=C(C=C2)N)=O)C1=C/F.O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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