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Biological Activity
Tezosentan (RO 610612) is an endothelin (ET) receptor antagonist, with pA2s of 9.5, 7.7 for ETA and ETB receptors, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 16.51 mL | 82.56 mL | 165.12 mL |
| 0.5 mM | 3.3 mL | 16.51 mL | 33.02 mL |
| 1 mM | 1.65 mL | 8.26 mL | 16.51 mL |
| 5 mM | 0.33 mL | 1.65 mL | 3.3 mL |
*The above data is based on the productmolecular weight 605.63. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A21118 |
|---|---|
| Actions | Antagonist |
| CAS No. | 180384-57-0 |
| Formula | C27H27N9O6S |
| M. Wt | 605.63 |
| Purity | >98% |
| Synonyms | RO 610612, RO610612, RO-610612 |
| SMILES | O=S(C1=NC=C(C(C)C)C=C1)(NC2=NC(C3=CC(C4=NNN=N4)=NC=C3)=NC(OCCO)=C2OC5=CC=CC=C5OC)=O |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
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