Fig. 1 · Structure

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Tezusomant

Growth Hormone Receptor Antagonist

Tezusomant is a growth hormone receptor antagonist that effectively inhibits the activity of growth hormone. This compound is instrumental in investigating conditions related to excessive growth hormone secretion, such as acromegaly and related endocrine disorders. Tezusomant facilitates research aimed at understanding the underlying mechanisms of these diseases and exploring potential therapeutic interventions.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 2802416-72-2
Applications Growth Hormone Receptor Antagonist
Formula C120H171N23O32S
Molecular Weight 2479.84
SMILES
O=C1[C@@]2(CC=3C=4C(N(C3)CC(=O)NCCCC[C@](N(C)C(=O)[C@H](CC5=CC=C(C(O)=O)C=C5)NC(=O)CSC[C@@H](C(NCCCC[C@H](NC(CC[C@H](NC(CC[C@H](NC(CCCCCCCCCCCCCCC(O)=O)=O)C(O)=O)=O)C(O)=O)=O)C(N)=O)=O)NC(=O)[C@H]([C@H](C)C)NC(=O)C(C)(C)NC(=O)[C@H](CC=6C=7C(NC6)=CC=C(O)C7)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CC8=CC=C(C(O)=O)C=C8)N1)(C(=O)N[C@@H]([C@@H](C)C)C(=O)N[C@@H]([C@H](C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC(N)=O)C(=O)N2)[H])=CC=CC4)[H]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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