Fig. 1 · Structure
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TFEB activator 1
TFEB Activator
TFEB Activator 1 is an orally bioavailable compound that acts as a potent activator of Transcription Factor EB (TFEB) via an mTOR-independent mechanism. It effectively promotes the nuclear translocation of TFEB with an EC50 of 2167 nM. This activator enhances autophagy and holds potential for therapeutic applications in neurodegenerative diseases, making it a valuable tool for research in cellular homeostasis and related disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 39777-61-2 |
| Applications | TFEB Activator |
| Formula | C19H18O3 |
| Molecular Weight | 294.34 |
| SMILES | O=C(/C=C/C1=CC=CC=C1OC)/C=C/C2=CC=CC=C2OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.