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TG-100435

Tyrosine Kinase Inhibitor

TG-100435 is a multitargeted, orally active protein tyrosine kinase inhibitor, effectively engaging multiple kinases with Ki values ranging from 13 to 64 nM for Src, Lyn, Abl, Yes, Lck, and EphB4. This compound is crucial for cancer research, as it contributes to understanding the role of tyrosine kinases in tumor progression and the therapeutic potential of selective inhibition in cancer treatment strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	867330-68-5
Applications	Tyrosine Kinase Inhibitor
Formula	C₂₆H₂₅Cl₂N₅O
Molecular Weight	494.42
SMILES	ClC1=C(C2=CC3=C(C(C)=C2)N=C(NC4=CC=C(C=C4)OCCN5CCCC5)N=N3)C(Cl)=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.