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TGX-221

Catalog No.: A10923
PI3K Inhibitor
Adooq's TGX-221 has been cited by 4 publications
TGX-221 is a potent, selective, and cell permeable inhibitor of PI3K p110β.
TGX-221
Grouped product items
Size Price Stock Qty
1mg
$25.00
In stock
2mg
$40.00
In stock
5mg
$60.00
In stock
10mg
$90.00
In stock
25mg
$200.00
In stock
50mg
$350.00
In stock
100mg
$550.00
In stock
500mg
$1,255.00
In stock
10mM * 1mL in DMSO
$65.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's TGX-221 has been cited by 4 publications
  • Kevin J Pridham, .et al. , iScience, 2024, May 7;27(6):109921 PMID: 38812542
  • Mostafa Khater, .et al. , J Biol Chem, 2021, Jan-Jun, 296:100805 PMID: 34022220
  • Mostafa Khater, .et al. , J Biol Chem, 2021, Jan 22;296:100325 PMID: 33493514
  • Pridham KJ, .et al. , Neuro Oncol, 2018, Mar 27;20(4):494-505 PMID: 29016844
    • Biological Activity
    Discription TGX-221 is a potent, selective, and cell permeable inhibitor of PI3K p110β.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    Product Information
    Catalog Num A10923
    Formula C21H24N4O2
    Molecular Weight 364.4
    CAS Number 663619-89-4
    SMILES CC1=CN2C(=O)C=C(N=C2C(=C1)C(C)NC3=CC=CC=C3)N4CCOCC4
    Synonyms TGX221
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
    Solubility
    In vitro (25°C) DMSO 11 mg/mL (30.18 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 27.44 mL 137.21 mL 274.42 mL
    0.5 mM 5.49 mL 27.44 mL 54.88 mL
    1 mM 2.74 mL 13.72 mL 27.44 mL
    5 mM 0.55 mL 2.74 mL 5.49 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

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      C2

      V2

    • Calculator Reset
    PI3K/Akt/mTOR > PI3K
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