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Publications citing Adooq Products
TGX-221 Citations (1)
- Pridham KJ, .et al. PIK3CB/p110汕 is a selective survival factor for glioblastoma, Neuro Oncol, 2018, Mar 27;20(4):494-505 PMID: 29016844
Chemical Information
| Catalog Num | A10923 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 364.4 |
| Formula | C21H24N4O2 |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 663619-89-4 |
| Synonyms | TGX221 |
| SMILES | CC1=CN2C(=O)C=C(N=C2C(=C1)C(C)NC3=CC=CC=C3)N4CCOCC4 |
| Chemical Name | 7-methyl-2-(4-morpholinyl)-9-[1-(phenylamino)ethyl]-4H-pyrido[1,2-a]pyrimidin-4-one |
Description |
TGX-221 is a potent, selective, and cell permeable inhibitor of PI3K p110β. | ||||||||||||||||||||||||||||||||||||||||
Targets |
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| Solubility (25°C) * | In vitro | DMSO | 12 mg/mL (32.92 mM) |
|---|---|---|---|
| Water | <1 mg/mL (<1 mM) | ||
| Ethanol | <1 mg/mL (<1 mM) | ||
| In vivo | 1% DMSO/30% polyethylene glycol/1% Tween 80 | 30 mg/mL | |
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.44 mL | 137.21 mL | 274.42mL |
| 0.5 mM | 5.49 mL | 27.44 mL | 54.88 mL |
| 1 mM | 2.74 mL | 13.72 mL | 27.44 mL |
| 5 mM | 0.55 mL | 2.74 mL | 5.49 mL |
*The above data is based on the productmolecular weight 364.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
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