TGX-221

Catalog No.: A10923
PI3K Inhibitor
TGX-221 is a potent, selective, and cell permeable inhibitor of PI3K p110β.
Grouped product items
Product Name Price Stock Qty
TGX-221 5mg
Special Price $36.00 Regular Price $45.00
In stock
TGX-221 10mg
Special Price $60.00 Regular Price $75.00
In stock
TGX-221 25mg
Special Price $120.00 Regular Price $150.00
In stock
TGX-221 100mg
Special Price $200.00 Regular Price $250.00
In stock
TGX-221 10mM * 1mL in DMSO
Special Price $73.60 Regular Price $92.00
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Important Notice: For research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Adooq's TGX-221 has been cited by 3 publications
  • Mostafa Khater, .et al. , J Biol Chem, 2021, Jan-Jun, 296:100805 PMID: 34022220
  • Mostafa Khater, .et al. , J Biol Chem, 2021, Jan 22;296:100325 PMID: 33493514
  • Pridham KJ, .et al. , Neuro Oncol, 2018, Mar 27;20(4):494-505 PMID: 29016844
  • Biological Activity
    Discription TGX-221 is a potent, selective, and cell permeable inhibitor of PI3K p110β.
    Targets
    Target Value
    Product Information
    Catalog Num A10923
    Formula C21H24N4O2
    Molecular Weight 364.4
    CAS Number 663619-89-4
    SMILES CC1=CN2C(=O)C=C(N=C2C(=C1)C(C)NC3=CC=CC=C3)N4CCOCC4
    Synonyms TGX221
    Storage

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    Solubility
    In vitro (25°C) DMSO 11 mg/mL (30.18 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 1% DMSO+30% polyethylene glycol+1% Tween 80 28 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 27.44 mL 137.21 mL 274.42 mL
    0.5 mM 5.49 mL 27.44 mL 54.88 mL
    1 mM 2.74 mL 13.72 mL 27.44 mL
    5 mM 0.55 mL 2.74 mL 5.49 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

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