TGX-221

Name: TGX-221
SKU: A10923
Price: 45 USD
Rating: 5 (4 reviews)

Catalog No.: A10923

PI3K Inhibitor

Adooq's TGX-221 has been cited by 4 publications

TGX-221 is a potent, selective, and cell permeable inhibitor of PI3K p110β.

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Grouped product items
Product Name	Price	Stock
TGX-221 5mg	$45.00	In stock
TGX-221 10mg	$75.00	In stock
TGX-221 25mg	$150.00	In stock
TGX-221 100mg	$250.00	In stock
*TGX-221 10mM 1mL in DMSO**	$92.00	In stock
Bulk Size	Bulk Discount

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Important Notice: For research use only. We do not sell to patients.

Data Sheet

SDS

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Adooq Products cited in reputable paper

Adooq's TGX-221 has been cited by 4 publications

Kevin J Pridham, .et al. , iScience, 2024, May 7;27(6):109921 PMID: 38812542

Mostafa Khater, .et al. , J Biol Chem, 2021, Jan-Jun, 296:100805 PMID: 34022220

Mostafa Khater, .et al. , J Biol Chem, 2021, Jan 22;296:100325 PMID: 33493514

Pridham KJ, .et al. , Neuro Oncol, 2018, Mar 27;20(4):494-505 PMID: 29016844

Biological Activity

Discription

TGX-221 is a potent, selective, and cell permeable inhibitor of PI3K p110β.

Targets

Target	Value

Product Information

Catalog Num	A10923
Formula	C21H24N4O2
Molecular Weight	364.4
CAS Number	663619-89-4
SMILES	CC1=CN2C(=O)C=C(N=C2C(=C1)C(C)NC3=CC=CC=C3)N4CCOCC4
Synonyms	TGX221
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Solubility

In vitro (25°C)	DMSO	11 mg/mL (30.18 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	27.44 mL	137.21 mL	274.42 mL
0.5 mM	5.49 mL	27.44 mL	54.88 mL
1 mM	2.74 mL	13.72 mL	27.44 mL
5 mM	0.55 mL	2.74 mL	5.49 mL

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