Fig. 1 · Structure
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TH10785
OGG1 Activator
TH10785 is an OGG1 (8-oxoguanine glycosylase 1) activator that enhances enzymatic activity by interacting with specific amino acids, phenylalanine-319 and glycine-42. This compound facilitates β, δ-lyase functions, allowing for effective processing of oxidative DNA lesions. TH10785 is valuable for research into diseases associated with DNA damage and the aging process, providing insights into cellular repair mechanisms and potential therapeutic targets.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 1002801-51-5 |
| Applications | OGG1 Activator |
| Formula | C17H21N3 |
| Molecular Weight | 267.37 |
| SMILES | C1(N=C(C2CC2)N=C3NC4CCCCC4)=C3C=CC=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.