Fig. 1 · Structure

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TH301

CRY2 Stabilizer

TH301 is a phenylpyrazole derivative that acts as a selective stabilizer of CRY2 (cryptochrome 2). This compound has been shown to dose-dependently prolong the circadian period, making it a valuable tool for researchers studying circadian rhythm regulation and its associated pathways. Its targeted action on CRY2 presents opportunities for investigations into the molecular mechanisms underlying circadian biology.

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Specifications

Manufacturer Adooq Bioscience
Actions Stabilizer
CAS Number 450338-32-6
Applications CRY2 Stabilizer
Formula C24H24ClN3O4S
Molecular Weight 485.98
SMILES
O=C(C1(C2=CC=C(Cl)C=C2)CCCC1)NC3=C4C(CS(C4)(=O)=O)=NN3C5=CC=C(OC)C=C5

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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