Fig. 1 · Structure
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Thailanstatin C
Pre-mRNA Splicing Inhibitor
Thailanstatin C is an inhibitor of pre-mRNA splicing, with an IC50 value of 6.84 μM, derived from Burkholderia thailandensis MSMB43. This compound exhibits antiproliferative activity and is valuable for research applications focusing on the modulation of gene expression and the investigation of splicing mechanisms in eukaryotic cells.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1426953-24-3 |
| Applications | Pre-mRNA Splicing Inhibitor |
| Formula | C30H46ClNO9 |
| Molecular Weight | 600.14 |
| SMILES | C[C@@H](C[C@H]([C@H](O1)C)NC(/C=C\[C@H](C)OC(C(C)C)=O)=O)[C@@H]1C/C=C(C)/C=C/[C@@H]2[C@H]([C@@](O)(C[C@H](O2)CC(O)=O)CCl)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.