Thalidomide-1-Me,5-F

Catalog No.: A80582
E3 Ligase Activator
Thalidomide-1-Me,5-F is a fluorinated E3 ligase activator that functions by promoting the ubiquitination of target proteins. This compound exhibits key biological activity in modulating protein degradation pathways, making it valuable for research in cellular signaling and therapeutic interventions. Additionally, Thalidomide-1-Me,5-F can serve as a substrate for further derivatization via nucleophilic aromatic substitution (SNAr) reactions.
Grouped product items
Size Price Stock Qty
100mg
$25.00
In stock
250mg
$50.00
In stock
500mg
$80.00
In stock
1g
$125.00
In stock
5g
$350.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionThalidomide-1-Me,5-F is a fluorinated E3 ligase activator that functions by promoting the ubiquitination of target proteins. This compound exhibits key biological activity in modulating protein degradation pathways, making it valuable for research in cellular signaling and therapeutic interventions. Additionally, Thalidomide-1-Me,5-F can serve as a substrate for further derivatization via nucleophilic aromatic substitution (SNAr) reactions.
Product Information
Catalog NumA80582
FormulaC14H11FN2O4
Molecular Weight290.25
CAS Number2230957-36-3
SMILESO=C1N(C(CC2)C(N(C)C2=O)=O)C(C3=C1C=CC(F)=C3)=O
Useful Calculator

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