Thalidomide-1-Me-5-NH2

Catalog No.: A80560
Thalidomide Analog
Thalidomide-1-Me-5-NH2 is an aminated analog of Thalidomide, primarily targeting E3 ligase activation. This compound serves as a useful intermediate for the development of PROTAC (Proteolysis Targeting Chimera) molecules through amine derivatization. Researchers can utilize this reagent in studies focused on targeted protein degradation and related therapeutic applications.
Grouped product items
Size Price Stock Qty
25mg
$185.00
In stock
50mg
$285.00
In stock
100mg
$430.00
In stock
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionThalidomide-1-Me-5-NH2 is an aminated analog of Thalidomide, primarily targeting E3 ligase activation. This compound serves as a useful intermediate for the development of PROTAC (Proteolysis Targeting Chimera) molecules through amine derivatization. Researchers can utilize this reagent in studies focused on targeted protein degradation and related therapeutic applications.
Product Information
Catalog NumA80560
FormulaC14H13N3O4
Molecular Weight287.27
CAS Number1468761-60-5
SMILESO=C1N(C(CC2)C(N(C)C2=O)=O)C(C3=C1C=CC(N)=C3)=O
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