Fig. 1 · Structure
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Thalidomide-(2)piperidine
E3 Ligase Ligand
Thalidomide-(2)piperidine is a potent E3 ligase ligand that plays a critical role in targeted protein degradation. This compound is valuable for the synthesis of proteolysis-targeting chimeras (PROTACs), facilitating the selective degradation of proteins of interest in cellular models. Its unique mechanism of action makes it a powerful tool in chemical biology and drug discovery research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Ligand / Binder |
| CAS Number | 2616553-33-2 |
| Applications | E3 Ligase Ligand |
| Formula | C16H16ClN3O4 |
| Molecular Weight | 349.77 |
| SMILES | O=C(C1=C2C=C3CNCCC3=C1)N(C(CC4)C(NC4=O)=O)C2=O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.