Fig. 1 · Structure
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Thalidomide-4,5-F
Thalidomide Analog
Thalidomide-4,5-F is a fluorinated analogue of Thalidomide, primarily acting through the promotion of protein ubiquitinylation. This modification can enhance the degradation of target proteins, making it a valuable tool for research in cellular regulation and signaling pathways. The compound's unique fluorinated structure allows for further derivatization at the fluorine sites, expanding its potential applications in medicinal chemistry and pharmaceutical development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2222115-19-5 |
| Applications | Thalidomide Analog |
| Formula | C13H8F2N2O4 |
| Molecular Weight | 294.21 |
| SMILES | O=C1N(C(CC2)C(NC2=O)=O)C(C3=C1C=CC(F)=C3F)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.