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Thalidomide-4-carbaldehyde

Thalidomide Analog

Thalidomide-4-carbaldehyde is a Thalidomide analogue featuring an aldehyde functional group. This compound is known to recruit E3 ligases, facilitating the ubiquitination and subsequent proteolysis of target proteins, making it a valuable tool in studying protein degradation pathways. Its highly reactive aldehyde group engages in reductive amination reactions with amine nucleophiles, offering diverse applications in chemical biology and medicinal chemistry research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2369068-46-0
Applications	Thalidomide Analog
Formula	C₁₄H₁₀N₂O₅
Molecular Weight	286.24
SMILES	O=CC1=CC=CC(C(N2C(CC3)C(NC3=O)=O)=O)=C1C2=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.