Thalidomide-4-F,5-Br

Catalog No.: A81222
Thalidomide Analog
Thalidomide-4-F,5-Br is a Thalidomide analogue designed to enhance E3 ligase recruitment for the ubiquitination and subsequent degradation of target proteins. This compound exhibits potential biological activity in modulating protein turnover, making it a valuable tool in diverse research applications, including cancer studies and the investigation of cellular signaling pathways. Furthermore, the presence of fluorine and bromine allows for further derivatization, enabling the exploration of new molecular properties and activities.
Grouped product items
Size Price Stock Qty
25mg
$110.00
In stock
50mg
$170.00
In stock
100mg
$255.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionThalidomide-4-F,5-Br is a Thalidomide analogue designed to enhance E3 ligase recruitment for the ubiquitination and subsequent degradation of target proteins. This compound exhibits potential biological activity in modulating protein turnover, making it a valuable tool in diverse research applications, including cancer studies and the investigation of cellular signaling pathways. Furthermore, the presence of fluorine and bromine allows for further derivatization, enabling the exploration of new molecular properties and activities.
Product Information
Catalog NumA81222
FormulaC13H8BrFN2O4
Molecular Weight355.12
CAS Number2740657-28-5
SMILESO=C1NC(C(CC1)N2C(C3=CC=C(C(F)=C3C2=O)Br)=O)=O
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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