Thalidomide-4-OH-(S)-CH3 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of cereblon to target proteins, enabling the formation of PROTACs (proteolysis-targeting chimeras) when linked to target protein ligands via appropriate linkers. Its ability to modulate protein degradation pathways makes it valuable for research applications in targeted protein degradation and therapeutic development.
Thalidomide-4-OH-(S)-CH3 is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of cereblon to target proteins, enabling the formation of PROTACs (proteolysis-targeting chimeras) when linked to target protein ligands via appropriate linkers. Its ability to modulate protein degradation pathways makes it valuable for research applications in targeted protein degradation and therapeutic development.
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