Thalidomide-5-F-6-I is a specific ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be conjugated to target protein ligands through a linker, enabling the development of PROTACs for targeted protein degradation. Its applications include drug discovery and the investigation of protein regulation mechanisms.
Thalidomide-5-F-6-I is a specific ligand for the E3 ubiquitin ligase cereblon (CRBN), facilitating the recruitment of the cereblon protein. This compound can be conjugated to target protein ligands through a linker, enabling the development of PROTACs for targeted protein degradation. Its applications include drug discovery and the investigation of protein regulation mechanisms.
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