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Thalidomide-5-NH-C9-acid

E3 Ligase Ligand-linker Conjugate

Thalidomide-5-NH-C9-acid is a synthetic E3 ligase ligand-linker conjugate that incorporates a Thalidomide-derived Cereblon ligand. This compound functions as a critical tool for studying targeted protein degradation through the ubiquitin-proteasome pathway. Its unique structure facilitates the conjugation of E3 ligase, making it suitable for research applications in drug development and the exploration of protein-protein interactions.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2473267-89-7
Applications	E3 Ligase Ligand-linker Conjugate
Formula	C₂₃H₂₉N₃O₆
Molecular Weight	443.50
SMILES	O=C(O)CCCCCCCCCNC1=CC=C2C(=O)N(C(=O)C2=C1)C3C(=O)NC(=O)CC3

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.