Fig. 1 · Structure
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Thalidomide-5-NH2-CH2-COOH
TRK Inhibitor
Thalidomide-5-NH2-CH2-COOH is a selective inhibitor of tropomyosin receptor kinase (Trk), targeting critical signaling pathways involved in various cellular processes. This compound acts as a ligand for E3 ligase, demonstrating significant potential in the study of diseases related to Trk signaling dysregulation. Its unique properties make it a valuable tool for researchers investigating therapeutic strategies in oncology and neurodegenerative disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2412056-27-8 |
| Applications | TRK Inhibitor |
| Formula | C15H13N3O6 |
| Molecular Weight | 331.28 |
| SMILES | O=C1N(C2CCC(NC2=O)=O)C(C3=C1C=C(NCC(O)=O)C=C3)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.