Fig. 1 · Structure
Documents & Downloads
Thalidomide-iodo
E3 Ligase Activator
Thalidomide-iodo is an iodo-substituted E3 ligase activator. It plays a crucial role in the ubiquitin-proteasome pathway, facilitating targeted protein degradation. Thalidomide-iodo can serve as a valuable intermediate for further chemical modifications, allowing researchers to explore novel derivatives in the study of protein regulation and cellular processes. This compound is essential for investigations into therapeutic strategies related to various diseases, including cancer and immune disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Activator |
| CAS Number | 2509137-01-1 |
| Applications | E3 Ligase Activator |
| Formula | C13H9IN2O4 |
| Molecular Weight | 384.13 |
| SMILES | O=C1C2=CC=C(C=C2C(N1C3C(NC(CC3)=O)=O)=O)I |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.