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Thalidomide-pyrrolidine

Ligands for E3 Ligase

Thalidomide-pyrrolidine is a ligand for E3 ligases, facilitating targeted protein degradation via the PROTAC technology. This compound is instrumental in the synthesis of PROTAC ARD-1676, which enables selective modulation of protein levels in cellular systems. Thalidomide-pyrrolidine is valuable for research applications focused on therapeutic interventions in various diseases by leveraging the ubiquitin-proteasome pathway.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Ligand / Binder
CAS Number	2616540-83-9
Applications	Ligands for E3 Ligase
Formula	C₁₅H₁₃N₃O₄
Molecular Weight	299.28
SMILES	O=C1NC(C(CC1)N2C(C3=C(C2=O)C=C(CNC4)C4=C3)=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.