Thalidomide-SH is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of cereblon to target proteins, enabling targeted protein degradation through PROTAC technology. Thalidomide-SH serves as a versatile tool in chemical biology and drug discovery, offering potential applications in studying protein regulation and developing new therapeutic strategies.
Thalidomide-SH is a selective ligand for the E3 ubiquitin ligase cereblon (CRBN). This compound facilitates the recruitment of cereblon to target proteins, enabling targeted protein degradation through PROTAC technology. Thalidomide-SH serves as a versatile tool in chemical biology and drug discovery, offering potential applications in studying protein regulation and developing new therapeutic strategies.
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