Fig. 1 · Structure
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Theaflavin-3-gallate
Anticancer Agent
Theaflavin-3-gallate is a prominent monomer derived from black tea that serves as an anticancer agent. It demonstrates prooxidant activity, inducing oxidative stress in carcinoma cells, particularly by interacting with reduced glutathione (GSH) in a concentration- and time-dependent manner. Theaflavin-3-gallate is known to promote apoptosis and G1 phase cell cycle arrest in ovarian cancer A2780/CP70 cells via p53-dependent pathways, while also causing DNA damage through the ATM/Chk/p53 signaling cascade. This compound is valuable for research applications focused on cancer biology and chemotherapeutic development.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 30462-34-1 |
| Applications | Anticancer Agent |
| Formula | C36H28O16 |
| Molecular Weight | 716.60 |
| SMILES | O=C(O[C@H]1[C@@H](C(C=C2O)=CC3=C([C@@H]4[C@H](O)CC5=C(O)C=C(O)C=C5O4)C=C(O)C(O)=C3C2=O)OC6=CC(O)=CC(O)=C6C1)C7=CC(O)=C(O)C(O)=C7 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.