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Theliatinib

Catalog No.: A22215
EGFR inhibitor
Theliatinib (HMPL-309) is a potent, ATP-competitive, orally active and highly selective EGFR inhibitor with a Ki of 0.05 nM and an IC50 of 3 nM.
Theliatinib
Grouped product items
Product Name Price Stock Qty
Theliatinib 5mg
$216.00
In stock
Theliatinib 10mg
$372.00
In stock
Theliatinib 50mg
$1,104.00
In stock
Theliatinib 100mg
$2,160.00
In stock
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Important Notice: For research use only. We do not sell to patients.

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Biological Activity
Discription Theliatinib (HMPL-309) is a potent, ATP-competitive, orally active and highly selective EGFR inhibitor with a Ki of 0.05 nM and an IC50 of 3 nM.
Product Information
Catalog Num A22215
Formula C25H26N6O2
Molecular Weight 442.51
CAS Number 1353644-70-8
SMILES O=C(N1C[C@]2([H])N(C)CC[C@]2([H])C1)NC3=CC4=C(NC5=CC=CC(C#C)=C5)N=CN=C4C=C3OC
Synonyms HMPL-309
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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    C2

    V2

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Protein Tyrosine Kinases > EGFR/HER2
Angiogenesis > EGFR/HER2
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