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Theralizumab
Theralizumab (TGN1412) is a humanized IgG4 monoclonal antibody with superagonistic properties targeting CD28. It directly stimulates T-cell activation, which can lead to cytokine release syndrome (CRS). This antibody is primarily utilized in research focused on understanding and potentially treating rheumatoid arthritis.
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Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 906068-56-2 |
| Molecular Weight | 145620 |
| Synonyms | TGN1412 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.