Fig. 1 · Structure
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Thiamine triphosphoric acid ester
Neuroactive Compound
Thiamine triphosphoric acid ester, also known as thiamine triphosphate (ThTP), functions as a neuroactive compound involved in cellular metabolism and signal transduction. This triphosphate derivative of vitamin B1 is found across various biological systems, including microorganisms, animal organs, and plants. In Escherichia coli, ThTP is synthesized transiently under amino acid deficiency conditions, while in mammalian cells, it is produced continuously at low levels. It is synthesized through the actions of enzymes such as cytosolic adenylate kinase 1 (AK1) and FoF1-ATP synthase present in brain mitochondria, underscoring its significance in fundamental biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 3475-65-8 |
| Applications | Neuroactive Compound |
| Formula | C12H19N4O10P3S |
| Molecular Weight | 504.29 |
| Synonyms | Thiamine triphosphate |
| SMILES | O=P(O)(OP(O)(OP([O-])(OCCC1=C(C)[N+](CC2=CN=C(C)N=C2N)=CS1)=O)=O)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
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| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.