Fig. 1 · Structure
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Thiazinamium chloride
TxB2 Inhibitor
Thiazinamium chloride is a TxB2 inhibitor that exhibits potent anticholinergic and antiallergic activities, with an IC50 value of 0.2 µM for the inhibition of TxB2 synthesis. This compound is structurally related to H-1 antagonists, such as Promethazine. Additionally, Thiazinamium chloride stimulates phosphatidylcholine secretion in adult rat type II pneumocytes, making it valuable for research in respiratory and inflammatory pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 4320-13-2 |
| Applications | TxB2 Inhibitor |
| Formula | C18H23ClN2S |
| Molecular Weight | 334.91 |
| SMILES | C[N+](C)(C)C(C)CN1C2=C(C=CC=C2)SC3=CC=CC=C13.[Cl-] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.