Fig. 1 · Structure
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Thiethylperazine dimaleate
Anti-emetic Agent
Thiethylperazine dimaleate is a phenothiazine derivative that functions as a potent antagonist of dopamine D2 and histamine H1 receptors. This compound demonstrates significant anti-emetic properties and has been shown to selectively activate ABCC1, leading to a reduction in amyloid-β (Aβ) load in murine models. Additionally, thiethylperazine dimaleate exhibits antipsychotic and antimicrobial activities, making it a valuable reagent for various biological research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1179-69-7 |
| Applications | Anti-emetic Agent |
| Formula | C30H37N3O8S2 |
| Molecular Weight | 631.76 |
| SMILES | CN1CCN(CCCN2C3=C(C=CC=C3)SC4=CC=C(SCC)C=C24)CC1.O=C(O)/C=C\C(O)=O.O=C(O)/C=C\C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.