Fig. 1 · Structure
Documents & Downloads
THIIC
mGluR Agonist
THIIC (LY2607540) is a positive allosteric modulator of metabotropic glutamate receptors (mGluRs). This compound exhibits significant anxiolytic and antidepressant-like activities in various animal models, making it a valuable tool for studying anxiety and depression mechanisms. Additionally, THIIC impacts sleep patterns and induces neurochemical alterations, providing further insights into its pharmacological profile and potential therapeutic applications in neuropsychiatric disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 1204737-09-6 |
| Applications | mGluR Agonist |
| Formula | C24H24F3N3O4 |
| Molecular Weight | 475.46 |
| Synonyms | LY2607540 |
| SMILES | O=C(NCC1=CC=C(C=C1)COC2=CC=C(C(O)=C2C(F)(F)F)C(C(C)C)=O)C3=CN(C=N3)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.