Thioether-cyclized helix B peptide, CHBP

Name: Thioether-cyclized helix B peptide, CHBP
Brand: Adooq Bioscience
SKU: A79751
Rating: 5 (288 reviews)

Catalog No.: A79751

Peptide

Thioether-cyclized helix B peptide, CHBP, targets the mTOR signaling pathway to modulate autophagy. This peptide enhances metabolic stability and exhibits renoprotective effects by inhibiting mTORC1 while activating mTORC2. Its unique properties make it a valuable reagent for researching cellular metabolism and kidney protection mechanisms.

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Thioether-cyclized helix B peptide, CHBP 1453840-35-1 Peptide

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Biological Activity

Description	Thioether-cyclized helix B peptide, CHBP, targets the mTOR signaling pathway to modulate autophagy. This peptide enhances metabolic stability and exhibits renoprotective effects by inhibiting mTORC1 while activating mTORC2. Its unique properties make it a valuable reagent for researching cellular metabolism and kidney protection mechanisms.

Product Information

Catalog Num	A79751
Formula	C56H93N19O22S
Molecular Weight	1416.52
CAS Number	1453840-35-1
Sequence	Ac-GIn-Glu-GIn-Leu-Glu-Arg-Ala-Leu-Asn-Ser-Ser-Cys-NH2 (Cyclization via thioether-bond through N-terminal Me and -SH of Cys)
Sequence shortening	Ac-QEQLERALNSSC-NH2 (Cyclization via thioether-bond through N-terminal Me and -SH of Cys)
SMILES	C(CC(N)=O)[C@@H]1NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)CSC[C@@H](C(N)=O)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](CC(C)C)NC1=O

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