Thioridazine 2-Sulfone-d3

Catalog No.: A32924
Stable Isotope
Thioridazine 2-Sulfone-d3 is a stable isotope-labeled analog of Thioridazine hydrochloride, an antagonist of the dopamine D2 receptor family. This compound demonstrates significant anti-psychotic and anti-anxiety properties and exerts potent inhibition of the PI3K-Akt-mTOR signaling pathway, contributing to its anti-angiogenic effects. Additionally, Thioridazine hydrochloride has been shown to induce antiproliferative effects and promote apoptosis in various cancer cell types, particularly targeting cancer stem cells (CSCs), making it a valuable tool for cancer research and neurological studies.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
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Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionThioridazine 2-Sulfone-d3 is a stable isotope-labeled analog of Thioridazine hydrochloride, an antagonist of the dopamine D2 receptor family. This compound demonstrates significant anti-psychotic and anti-anxiety properties and exerts potent inhibition of the PI3K-Akt-mTOR signaling pathway, contributing to its anti-angiogenic effects. Additionally, Thioridazine hydrochloride has been shown to induce antiproliferative effects and promote apoptosis in various cancer cell types, particularly targeting cancer stem cells (CSCs), making it a valuable tool for cancer research and neurological studies.
Product Information
Catalog NumA32924
FormulaC21H23D3N2O2S2
Molecular Weight405.59
CAS Number1329652-09-6
SMILESC(CC1N(C([2H])([2H])[2H])CCCC1)N2C=3C(SC=4C2=CC=CC4)=CC=C(S(C)(=O)=O)C3
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