Fig. 1 · Structure
Documents & Downloads
Thiosildenafil
Sildenafil Analogue
Thiosildenafil is a synthetic analogue of Sildenafil, primarily targeting phosphodiesterase type 5 (PDE5). This compound exhibits potent vasodilatory effects by enhancing the levels of cyclic guanosine monophosphate (cGMP) in vascular smooth muscle. Thiosildenafil has applications in researching erectile dysfunction and pulmonary hypertension, making it a valuable tool for investigations into cardiovascular health and related therapeutic approaches.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 479073-79-5 |
| Applications | Sildenafil Analogue |
| Formula | C22H30N6O3S2 |
| Molecular Weight | 490.64 |
| SMILES | S=C1C2=C(N=C(N1)C3=C(C=CC(S(=O)(N4CCN(CC4)C)=O)=C3)OCC)C(CCC)=NN2C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.