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THP1 Lipid

Ionizable Lipidoid

THP1 Lipid is an ionizable lipidoid designed for the synthesis of lipid nanoparticles (LNPs) to facilitate mRNA delivery to muscle tissue. This reagent demonstrates minimal toxicity and enables targeted gene editing in specific liver tissues within a tdTomato transgenic mouse model. THP1 Lipid is applicable in vaccine delivery systems and CRISPR/Cas9-mediated gene editing research, making it a valuable tool for genetic studies and therapeutic applications.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	3097638-13-3
Applications	Ionizable Lipidoid
Formula	C₂₆H₄₈N₂O₄
Molecular Weight	452.67
SMILES	O=C(C1=C(N(CN(C1)CCCCCCCC)CCCCCCCC)C(OCC)=O)OCC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.