Fig. 1 · Structure

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Threo-dihydrobupropion

Bupropion Metabolite

Threo-dihydrobupropion is a significant metabolite of bupropion, produced through oxidative and reductive processes. It exhibits pharmacological activity that may contribute to the therapeutic effects of bupropion, which functions as a dual inhibitor of dopamine and norepinephrine uptake, as well as a nicotine receptor antagonist. This compound is valuable for research into depression treatment and smoking cessation strategies.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 153365-82-3
Applications Bupropion Metabolite
Formula C13H20ClNO
Molecular Weight 241.76
SMILES
CC(C)(C)N[C@H](C)[C@@H](C1=CC(Cl)=CC=C1)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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