Fig. 1 · Structure
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THX-B
p75NTR Antagonist
THX-B is a potent non-peptidic antagonist of the neurotrophin receptor p75NTR. This compound is utilized in research investigating the mechanisms of diabetic kidney disease, as well as neurodegenerative and inflammatory disorders. Its ability to selectively inhibit p75NTR provides valuable insights into these pathological conditions, making it a key reagent for related studies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1372206-64-8 |
| Applications | p75NTR Antagonist |
| Formula | C16H24N6O4 |
| Molecular Weight | 364.40 |
| SMILES | O=C(N(C(C)C)C(NC(C)C)=O)CN1C=NC(N(C)C(N2C)=O)=C1C2=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.