Fig. 1 · Structure
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Tibesaikosaponin V
Nuclear Transcription Factor Inhibitor
Tibesaikosaponin V is a triterpene diglycoside that functions as a nuclear transcription factor inhibitor. It effectively suppresses the mRNA expression of key nuclear transcription factors, including peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer binding protein α (C/EBPα), thereby inhibiting the differentiation of 3T3-L1 preadipocytes and reducing lipid accumulation without cytotoxic effects on adipocytes. This compound is valuable for research studies focused on obesity and associated metabolic disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2319668-87-4 |
| Applications | Nuclear Transcription Factor Inhibitor |
| Formula | C42H68O15 |
| Molecular Weight | 812.98 |
| Synonyms | TKV |
| SMILES | C[C@]12C([C@@]3([H])[C@@](C([C@@H]1O)=O)(CCC(C)(C3)C)CO)=C[C@H]([C@@]4([H])[C@]2(CC[C@]5([H])[C@@]4(CC[C@@H]([C@@]5(C)CO)O[C@H]6[C@@H]([C@H]([C@H]([C@H](O6)C)O)O[C@@H]7O[C@@H]([C@H]([C@@H]([C@H]7O)O)O)CO)O)C)C)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.