Fig. 1 · Structure
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TIBI
Rio1 Inhibitor
TIBI is a potent ATP-competitive inhibitor of the Rio1 enzyme, exhibiting an IC50 of 0.09 μM and a Ki of 0.05 μM. This compound is known to enhance the thermostability of Rio1, making it a valuable tool in studying ribosome biogenesis and associated pathways. Researchers can utilize TIBI to investigate the role of Rio1 in cellular processes and its potential implications in disease models.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1196457-06-3 |
| Applications | Rio1 Inhibitor |
| Formula | C7H2I4N2 |
| Molecular Weight | 621.72 |
| SMILES | IC1=C2C(N=CN2)=C(C(I)=C1I)I |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.