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Tibremciclib

CDK Inhibitor

Tibremciclib is a selective inhibitor of cyclin-dependent kinase 4 (CDK4), exhibiting significant antineoplastic activity. By blocking CDK4 activity, it disrupts cell cycle progression and promotes apoptosis in cancer cells. Tibremciclib is primarily utilized in cancer research and therapeutic applications, focusing on targeting tumors driven by aberrant CDK4 signaling.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2397678-18-9
Applications	CDK Inhibitor
Formula	C₂₈H₃₂F₂N₈
Molecular Weight	518.60
SMILES	C[C@H]1N2C3=CC(C4=NC(NC5=CC=C(C=N5)CN6CCN(CC6)CC)=NC=C4F)=CC(F)=C3N=C2CCC1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.