Fig. 1 · Structure
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Tienilic acid
Diuretic Hypotensive Agent
Tienilic acid, a diuretic hypotensive agent, primarily functions by promoting increased urine output and decreased blood pressure. While demonstrating significant biological activity in managing hypertension, Tienilic acid has been noted to induce hepatotoxicity. This compound is metabolized into reactive electrophilic metabolites by cytochrome P450 (CYP) enzymes, which may contribute to its biological effects and safety profile in research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 40180-04-9 |
| Applications | Diuretic Hypotensive Agent |
| Formula | C13H8Cl2O4S |
| Molecular Weight | 331.18 |
| Synonyms | Ticrynafen; ANP 3624 |
| SMILES | O=C(O)COC1=CC=C(C(C2=CC=CS2)=O)C(Cl)=C1Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.