Fig. 1 · Structure
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Tiludronate disodium
Osteoregulator
Tiludronate disodium is an orally active bisphosphonate that functions as an osteoregulator, primarily targeting osteoclasts. It acts as a potent inhibitor of the osteoclast vacuolar H(+)-ATPase, demonstrating significant anti-resorptive and anti-inflammatory properties. This compound is utilized in research investigating metabolic bone disorders and the regulation of bone metabolism.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 149845-07-8 |
| Applications | Osteoregulator |
| Formula | C7H7ClNa2O6P2S |
| Molecular Weight | 362.57 |
| Synonyms | Tiludronic acid disodium |
| SMILES | O=P(O)(O[Na])C(P(O)(O[Na])=O)SC1=CC=C(Cl)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.