Fig. 1 · Structure
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TIM-3-IN-1
TIM-3 Inhibitor
TIM-3-IN-1 is a selective inhibitor of T-cell immunoglobulin and mucin-domain containing-3 (TIM-3), a checkpoint receptor involved in immune regulation. This compound demonstrates potential to enhance anti-tumor immune responses, making it a valuable tool for cancer immunotherapy research. Its application may provide insights into overcoming immune resistance in tumor microenvironments and evaluating TIM-3 engagement in various cancer types.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2883237-04-3 |
| Applications | TIM-3 Inhibitor |
| Formula | C20H16ClN7O3S |
| Molecular Weight | 469.90 |
| SMILES | CC1=NN2C(NC3=CC(Cl)=C(C4=C(C)C=C(NS(C5=NC=CN5)(=O)=O)C=C4)C=C3C2=N1)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.