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TIM-3-ligand-1

TIM-3 Ligand

TIM-3-ligand-1 is a highly selective antagonist of the TIM-3 receptor, exhibiting a Ki value of 156 nM. This compound plays a critical role in modulating immune responses and is particularly relevant in the study of immunotherapy applications. TIM-3-ligand-1 is instrumental in investigating the regulatory pathways of T cell exhaustion and could aid in the development of novel therapeutic strategies for cancer and autoimmune diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Antagonist
CAS Number	2883237-01-0
Applications	TIM-3 Ligand
Formula	C₁₈H₁₆ClN₅O₃S
Molecular Weight	417.87
SMILES	CS(=O)(NC1=CC=C(C2=CC3=C(NC(N4C3=NC(C)=N4)=O)C=C2Cl)C(C)=C1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.