Fig. 1 · Structure
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Tinlarebant
RBP4 Antagonist
Tinlarebant is an orally active antagonist of retinol-binding protein 4 (RBP4). This compound is primarily utilized in research related to Stargardt disease, a genetic condition that leads to progressive vision loss. Tinlarebant's ability to inhibit RBP4 presents potential avenues for exploring therapeutic strategies aimed at mitigating the effects of this disorder.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 1821327-95-0 |
| Applications | RBP4 Antagonist |
| Formula | C21H21F5N4O2 |
| Molecular Weight | 456.41 |
| Synonyms | LBS-008; BPN-14967 |
| SMILES | CC(N1CCC2=C(C1)NN=C2C(N3CCC(CC3)C4=CC=C(C(F)=C4C(F)(F)F)F)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.