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TIPARP-IN-1

PARP7 Inhibitor

TIPARP-IN-1 is a selective inhibitor of PARP7 (TIPARP) with an IC50 of 2.15 nM. By inhibiting TIPARP, this compound restores the interferon signaling pathway in tumors, effectively enhancing the anti-tumor immune response within the tumor microenvironment while minimizing systemic cytokine production. TIPARP-IN-1 is an important tool for investigating the role of PARP7 in head and neck squamous cell carcinoma.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3106183-96-1
Applications	PARP7 Inhibitor
Formula	C₂₂H₂₃F₆N₅O₂
Molecular Weight	503.44
SMILES	O=C([C@H]1C[C@@H](CC2=CNC(C(C(F)(F)F)=C2)=O)C1)N(C[C@H]3C)CCN3C4=NC=C(C(F)(F)F)C=N4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.